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William H. Bisson
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B. C. Goodale
,
La Du, J. K.
,
Tilton, F.
,
Sullivan, C. M.
,
Bisson, W. H.
,
Waters, K. M.
, and
Tanguay, R. L.
,
“
Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs
”
,
Toxicological Sciences
, vol. 147, no. 2, pp. 397 - 411, 2015.
M. F. Miller
,
Goodson, W. H.
,
Manjili, M. H.
,
Kleinstreuer, N.
,
Bisson, W. H.
, and
Lowe, L.
,
“
Low-Dose Mixture Hypothesis of Carcinogenesis Workshop: Scientific Underpinnings and Research Recommendations.
”
,
Environ Health Perspect
, 2017.
A. Sehrawat
,
Gao, L.
,
Wang, Y.
,
Bankhead, A.
,
McWeeney, S. K.
,
King, C. J.
,
Schwartzman, J.
,
Urrutia, J.
,
Bisson, W. H.
,
Coleman, D. J.
,
Joshi, S. K.
,
Kim, D. - H.
,
Sampson, D. A.
,
Weinmann, S.
,
Kallakury, B. V. S.
,
Berry, D. L.
,
Haque, R.
,
Van Den Eeden, S. K.
,
Sharma, S.
,
Bearss, J.
,
Beer, T. M.
,
Thomas, G. V.
,
Heiser, L. M.
, and
Alumkal, J. J.
,
“
LSD1 activates a lethal prostate cancer gene network independently of its demethylase function.
”
,
Proc Natl Acad Sci U S A
, 2018.
M
R. Nahta
,
Al-Mulla, F.
,
Al-Temaimi, R.
,
Amedei, A.
,
Andrade-Vieira, R.
,
Bay, S.
,
Brown, D. G.
,
Calaf, G. M.
,
Castellino, R. C.
,
Cohen-Solal, K. A.
, and
Bisson, W. H.
,
“
Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression
”
,
Carcinogenesis
, vol. 36, pp. S2–S18, 2015.
A. C. Chlebowski
,
Garcia, G. R.
,
La Du, J. K.
,
Bisson, W. H.
,
Truong, L.
,
SL, M. Simonich
, and
Tanguay, R. L.
,
“
Mechanistic investigations into the developmental toxicity of nitrated and heterocyclic PAHs.
”
,
Toxicol Sci
, 2017.
B. R Robey
,
Weisz, J.
,
Kuemmerle, N.
,
Salzberg, A. C.
,
Berg, A.
,
Brown, D. G.
,
Kubik, L.
,
Palorini, R.
,
Al-Mulla, F.
,
Al-Temaimi, R.
, and
Bisson, W. H.
,
“
Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?
”
,
Carcinogenesis
, vol. 36, pp. S203–S231, 2015.
W. H. Bisson
,
Koch, D. C.
,
O'Donnell, E. F.
,
Khalil, S. M.
,
Kerkvliet, N. I.
,
Tanguay, R. L.
,
Abagyan, R.
, and
Kolluri, S. Kumar
,
“
Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands
”
,
Journal of medicinal chemistry
, vol. 52, pp. 5635–5641, 2009.
W. H. Bisson
,
Koch, D. C.
,
Donnell, E. F. ’
,
Khalil, S. M.
,
Kerkvliet, N. I.
,
Tanguay, R. L.
,
Abagyan, R.
, and
Kolluri, S.
,
“
Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands
”
,
Journal of Medicinal Chemistry
, vol. 52, no. 18, pp. 5635 - 5641, 2009.
W. H. Bisson
,
Koch, D. C.
,
O'Donnell, E. F.
,
Khalil, S. M.
,
Kerkvliet, N. I.
,
Tanguay, R. L.
,
Abagyan, R.
, and
Kolluri, S. Kumar
,
“
Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands.
”
,
J Med Chem
, vol. 52, no. 18, pp. 5635-41, 2009.
W. H. Bisson
,
Abagyan, R.
, and
Cavasotto, C. N.
,
“
Molecular basis of agonicity and antagonicity in the androgen receptor studied by molecular dynamics simulations
”
,
Journal of Molecular Graphics and Modelling
, vol. 27, no. 4, pp. 452 - 458, 2008.
C. V. Gerlach
,
Das, S. R.
,
Volz, D. C.
,
Bisson, W. H.
,
Kolluri, S.
, and
Tanguay, R.
,
“
Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish
”
,
Aquatic Toxicology
, vol. 154, pp. 71–79, 2014.
C. V. Gerlach
,
Das, S. R.
,
Volz, D. C.
,
Bisson, W. H.
,
Kolluri, S.
, and
Tanguay, R. L.
,
“
Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish
”
,
Aquatic Toxicology
, vol. 154, pp. 71 - 79, 2014.
C. V. Gerlach
,
Das, S. R.
,
Volz, D. C.
,
Bisson, W. H.
,
Kolluri, S. K.
, and
Tanguay, R. L.
,
“
Mono-substituted isopropylated triaryl phosphate, a major component of Firemaster 550, is an AHR agonist that exhibits AHR-independent cardiotoxicity in zebrafish.
”
,
Aquat Toxicol
, vol. 154, pp. 71-9, 2014.
P
M. J. Nemec
,
Kim, H.
,
Marciante, A. B.
,
Barnes, R. C.
,
Hendrick, E. D.
,
Bisson, W. H.
,
Talcott, S. T.
, and
Mertens-Talcott, S. U.
,
“
Polyphenolics from mango (Mangifera indica L.) suppress breast cancer ductal carcinoma in situ proliferation through activation of AMPK pathway and suppression of mTOR in athymic nude mice.
”
,
J Nutr Biochem
, vol. 41, pp. 12-19, 2016.
W. Engström
,
Darbre, P.
,
Eriksson, S.
,
Gulliver, L.
,
Hultman, T.
,
Karamouzis, M. V.
,
Klaunig, J. E.
,
Mehta, R.
,
Moorwood, K.
,
Sanderson, T.
, and
Bisson, W. H.
,
“
The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling
”
,
Carcinogenesis
, vol. 36, pp. S38–S60, 2015.
S
S. Raduner
,
Bisson, W. H.
,
Abagyan, R.
,
Altmann, K. - H.
, and
Gertsch, J.
,
“
Self-assembling cannabinomimetics: supramolecular structures of N-alkyl amides
”
,
Journal of natural products
, vol. 70, pp. 1010–1015, 2007.
J. D. Chavez
,
Wu, J.
,
Bisson, W. H.
, and
Maier, C. S.
,
“
Site-specific proteomic analysis of lipoxidation adducts in cardiac mitochondria reveals chemical diversity of 2-alkenal adduction
”
,
Journal of proteomics
, vol. 74, pp. 2417–2429, 2011.
A. Dehner
,
Planker, E.
,
Gemmecker, G.
,
Broxterman, Q. B.
,
Bisson, W. H.
,
Formaggio, F.
,
Crisma, M.
,
Toniolo, C.
, and
Kessler, H.
,
“
Solution Structure, Dimerization, and Dynamics of a Lipophilic $\alpha$/310-Helical, C$\alpha$-Methylated Peptide. Implications for Folding of Membrane Proteins
”
,
Journal of the American Chemical Society
, vol. 123, pp. 6678–6686, 2001.
A. Perkins
,
Phillips, J. Lynne
,
Kerkvliet, N. I.
,
Tanguay, R.
,
Perdew, G. H.
,
Kolluri, S.
, and
Bisson, W. H.
,
“
A structural switch between agonist and antagonist bound conformations for a ligand-optimized model of the human aryl hydrocarbon receptor ligand binding domain
”
,
Biology
, vol. 3, pp. 645–669, 2014.
A. Perkins
,
Phillips, J. Lynne
,
Kerkvliet, N. I.
,
Tanguay, R. L.
,
Perdew, G. H.
,
Kolluri, S. K.
, and
Bisson, W. H.
,
“
A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain.
”
,
Biology (Basel)
, vol. 3, no. 4, pp. 645-69, 2014.
A. Perkins
,
Phillips, J. Lynne
,
Kerkvliet, N.
,
Tanguay, R.
,
Perdew, G.
,
Kolluri, S.
, and
Bisson, W. H.
,
“
A Structural Switch between Agonist and Antagonist Bound Conformations for a Ligand-Optimized Model of the Human Aryl Hydrocarbon Receptor Ligand Binding Domain
”
,
Biology
, vol. 399, no. 4, pp. 645 - 669, 2014.
Y. Zhang
,
Yan, T.
,
Sun, D.
,
Xie, C.
,
Zheng, Y.
,
Zhang, L.
,
Yagai, T.
,
Krausz, K. W.
,
Bisson, W. H.
,
Yang, X.
, and
Gonzalez, F. J.
,
“
Structure-activity relationships of the main bioactive constituents of Euodia ruticarpa on aryl hydrocarbon receptor activation and bile acid homeostasis
”
,
Drug Metabolism and Disposition
, p. dmd.117.080176, 2018.
I. A. Murray
,
Flaveny, C. A.
,
Chiaro, C. R.
,
Sharma, A. K.
,
Tanos, R. S.
,
Schroeder, J. C.
,
Amin, S. G.
,
Bisson, W. H.
,
Kolluri, S.
, and
Perdew, G. H.
,
“
Suppression of cytokine-mediated complement factor gene expression through selective activation of the Ah receptor with 3′, 4′-dimethoxy-$\alpha$-naphthoflavone
”
,
Molecular pharmacology
, vol. 79, pp. 508–519, 2011.
L. Mu
,
Drandarov, K.
,
Bisson, W. H.
,
Schibig, A.
,
Wirz, C.
,
P Schubiger, A.
, and
Westera, G.
,
“
Synthesis and binding studies of epibatidine analogues as ligands for the nicotinic acetylcholine receptors
”
,
European journal of medicinal chemistry
, vol. 41, pp. 640–650, 2006.
S. Tardy
,
Orsato, A.
,
Mologni, L.
,
Bisson, W. H.
,
Donadoni, C.
,
Gambacorti-Passerini, C.
,
Scapozza, L.
,
Gueyrard, D.
, and
Goekjian, P. G.
,
“
Synthesis and biological evaluation of benzo [4, 5] imidazo [1, 2-c] pyrimidine and benzo [4, 5] imidazo [1, 2-a] pyrazine derivatives as anaplastic lymphoma kinase inhibitors
”
,
Bioorganic & medicinal chemistry
, vol. 22, pp. 1303–1312, 2014.
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